There are two epistemic caesuras with consequences which have yet to be evaluated: the breaking off of Economy from Philosophy and the banishing of Metaphysics from the citadel of knowledge. There is no doubt on the cause. Rationalization and illuminist secularization have constituted the explosive mixture for the pairing of heterodox conceptualizations. If somewhat brutal yet with method, the combinatory function of nature has been diluted in order to force the creative self-referentiality. From extrovert relationing to introvert relativism this constituted the falling from completitude and universalism to fragmentarism and exceptionalism. It is this process which created the savants that cannot communicate with each other and the experiments that only explain themselves.