Abstract. There are three imperatives of the sense of life: life lived in society, work and love. All these imperatives of the human being life are concomitantly achieved in the family of faith and hoping to the better, family of work and family of love provided by institution of family. The world we live in is characterized by growing complexity, uncertainty and rapid changes in spiritual plan. Man is the witness of departure from the determinism. Perception of this reality raises the problem of re-spiritualization of human mind. In order to adapt ourselves to the changes brought out by the XXIth century, in the framework of those three families in which man loves, works and hopes, essential is to go forward from the “passive honesty” to the “active sincerity” to create those environment of coexistence and succession of human being business in which to fill safe and able to assume our responsabilities by creativity. From the perspective of filling a life lived in community, in our world there are normal performances of sense long-expected and abnormal and unwanted distorted meaning. As human resource, the natural-spiritual capital existing in the participants to the economic and social life is composed of the biologic inheritance, that is the natural capital of the individual life to which is added the traditional capital accumulated during the first seven years at home family when the rules and faith of the first social-familial environment are set up followed by the educational capital achieved through education along the sense of life over-covered by the capital of life experience get in the work family. Without knowing the causes of things which fade away the hope of fulfilling the joy to live the life, the ceaseless struggle only with their effects, even if it brings a little comfort it is far from be ever able to help us to work at the roots of the paradigm through which we see, know, interpret and understand the world in which we live. Re-spiritualization of human mind by creativity in the new transition era toward the society of the responsibility and liberty to think and act is also organic bounded to management of hope and need to learn what to do with ourselves, to learn to develop, dream and be all the time beyond the fear.

Keywords: life; work; love; re-spiritualization of mind; biologic inheritance; management of hope.